Volume : 10
Issue : 1
Clinical profile and prognosis of patients with acute kidney injury from a tertiary care hospital in south India
Priyashree R, Shyamsundar CM, Kumar NS
Pdf Page Numbers :- 16-19
Priyashree R1,*, Shyamsundar CM2, and Sunil Kumar N3
1Department of General Medicine, Bangalore Medical College and Research Institute, Bangalore, Karnataka-560002, India
2Department of Endocrinology, Andhra Medical College, Maharani Peta, Visakhapatnam, Andhra Pradesh 530002, India
3Department of General Medicine, Vijayanagara Institute of Medical Sciences, Bellary, Karnataka-583104, India
*Corresponding author: Dr. Priyashree R, Senior Resident, Department of General Medicine, Bangalore Medical College and Research Institute, Bangalore, Karnataka-560002, India. Mobile no.: +91 6304561974; Email: firstname.lastname@example.org
Received 4 October 2021; Revised 25 November 2021; Accepted 7 December 2021; Published 15 December 2021
Citation: Priyashree R, Shyamsundar CM, Kumar NS. Clinical profile and prognosis of patients with acute kidney injury from a tertiary care hospital in south India. J Med Sci Res. 2022; 10(1):16-19. DOI: http://dx.doi.org/10.17727/JMSR.2022/10-4
Copyright: © 2022 Priyashree R et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Introduction: Acute kidney injury (AKI) is associated with significant mortality and prognosis depends on spectrum of etiologies and management. There are regional differences in etiology and outcomes of AKI. This study was undertaken to determine clinical characteristics, etiologies of AKI, modality of treatment and prognosis of AKI in our cohort of population.
Methodology: This is a retrospective observational study conducted over a period of 6 months from a tertiary care hospital. All patients above 15 years admitted with AKI are included in the study. Clinical parameters, risk factors, cause of AKI (as per KDIGO criteria) and treatment received were studied. Patients with underlying chronic kidney disease (CKD), obstructive causes, drugs and toxin mediated AKI were excluded from the study.
Results: A total of 50 patients with AKI were studied in this period. The mean age of patient was 41 years with slightly predominant male patients. The common etiologies of AKI included: infections (48%), snake bite (18%), hepatorenal syndrome (18%), cardiorenal causes (10%), and rhabdomyolysis in 6%. Oliguria was most common symptom at presentation (46%) followed by fever and breathlessness. Dialysis was required in 22 patients. Dialysis was equally effective in infective and non-infective causes of AKI. Mean duration of hospital stay was 7.8±2.5 days. Two patients died during study period due to multiorgan failure.
Conclusion: Infections are common cause for AKI in this study. Renal replacement therapy is equally effective in both infective and non-infective causes of AKI with favourable prognosis.
Keywords: acute kidney injury; infections; hemodialysis; mortality