Tracheobronchial adenoid cystic carcinoma treated with radical radiochemotherapy: Case report and review of literature

Chira Ranjan Khadanga, Gangadhar Vajrala, Satish Rao I, Rajeev Ratan Jain

Pdf Page Numbers :- 142-145

Chira Ranjan Khadanga¹, Gangadhar Vajrala^2,*, Satish Rao I³ and Rajeev Ratan Jain⁴

¹Department of Radiation Oncology, Hemalata Hospital & Research Centre, Bhubaneswar, Odisha-751023, India

²Department of Radiation Oncology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India

³Department of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India

⁴Department of Radiotherapy, Regional Cancer Centre, PTJNM Medical College, Raipur, Chhattisgarh-492001, India

*Corresponding author: Dr. Gangadhar, MBBS, MDRT, MPH, CLRA, Radiation Oncologist, Department of Radiation Oncology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India. Email: gvajrala@gmail.com

Received 22 June 2017; Revised 31 August 2017; Accepted 15 September 2017; Published 25 September 2017

Citation: Khadanga CR, Vajrala G, Satishrao I, Jain RR. Tracheobronchial adenoid cystic carcinoma treated with radical radiochemotherapy: Case report and review of literature. J Med Sci Res. 2017; 5(4):142-145. DOI: http://dx.doi.org/10.17727/JMSR.2017/5-27

Copyright: © 2017 Khadanga CR, et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Adenoid cystic carcinoma (ACC) is a low-grade malignancy of the elderly but has shown aggressive behavior. It is most commonly found in minor salivary glands and rarely in lacrimal glands, tracheobronchial tree, lung parenchyma, breast, cervix, skin, esophagus, prostate. The standard of care of ACC is essentially surgery followed by post-operative adjuvant radiation therapy depending upon various adverse features. Here we report an unusual tracheo-bronchial ACC in a 32-year-old lady who was treated with radical radiotherapy under image guidance along with concurrent chemotherapy using intravenous cisplatin on weekly basis. Response evaluation with ¹⁸FDG PET-CECT three months after the completion of treatment showed complete response, and has also remained disease free clinically at 3 years follow-up, without any late radiation toxicity.

Keywords: adenoid cystic carcinoma; radiation therapy; ¹⁸FDG PET-CECT