Hyponatremia in sepsis and its association with SOFA score: An observational cross sectional study

Kumar S, Pratima K, Bhattacharya R, Ambedkar SN, Saini RP

Pdf Page Numbers :- 10-15

Sandeep Kumar¹, Kumari Pratima², Ranita Bhattacharya¹, Shivlok Narayan Ambedkar^1,* and Ram Pratap Saini¹

¹Department of Medicine, Vardhaman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029, India

²Department of Paediatrics, Deen Dayal Upadhayay Hospital, New Delhi-110064, India

*Corresponding author: Dr. Shivlok Narayan Ambedkar, MD, Associate Professor, Department of Medicine, Vardhaman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029, India. Email: drshivlokmd@gmail.com

Received 3 August 2022; Revised 2 November 2022; Accepted 16 November 2022; Published 25 November 2022

Citation: Kumar S, Pratima K, Bhattacharya R, Ambedkar SN, Saini RP. Hyponatremia in sepsis and its association with SOFA score: An observational cross sectional study. J Med Sci Res. 2023; 11(1):10-15. DOI: http://dx.doi.org/10.17727/JMSR.2023/11-3

Copyright: © 2023 Kumar S et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: Sepsis is the one of the leading causes of hospital admissions and death in India and hyponatremia in sepsis is known to be an independent risk factor for mortality. Aim of the study was to determine the prevalence of hyponatremia in sepsis and its association with SOFA (sequential organ failure assessment) score.

Methodology: This is an observational cross-sectional study in a tertiary hospital of New Delhi India. A total of 95 patients with sepsis and more than 18 years of age were enrolled in the study over 18 months period. Blood samples were drawn for estimation of serum sodium and other investigations within 24 hours of admission of patients presenting with sepsis or diagnosis of sepsis if it develops during the hospital stay.

Results: Prevalence of hyponatremia in sepsis patients were 69.47% (n=95). No significant association was seen in SOFA with severity of hyponatremia (p value >.05).

Conclusion: No statistically significant correlation was observed between SOFA score and presence of hyponatremia or the severity of hyponatremia in the study subjects. Hyponatremia is a common in sepsis patient.

Keywords: sepsis; hyponatremia; SOFA score; severe sepsis; hyponatremia in ICU